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This collection brings together influential papers by mathematicians exploring the research frontiers of topology, one of the most important developments of modern mathematics. The papers cover a wide range of topological specialties, including tools for the analysis of group actions on manifolds, calculations of algebraic K-theory, a result on analytic structures on Lie group actions, a presentation of the significance of Dirac operators in smoothing theory, a discussion of the stable topology of 4-manifolds, an answer to the famous question about symmetries of simply connected manifolds,...

One of the great achievements of contemporary mathematics is the new understanding of four dimensions. Michael Freedman and Frank Quinn have been the principals in the geometric and topological development of this subject, proving the Poincar and Annulus conjectures respectively. Recognition for this work includes the award of the Fields Medal of the International Congress of Mathematicians to Freedman in 1986. In Topology of 4-Manifolds these authors have collaborated to give a complete and accessible account of the current state of knowledge in this field. The basic material has been...

Neutrophils, the most abundant white cells in humans, serve as the primary cellular defense against infection. Neutrophil Methods and Protocols, Second Edition provides a concise set of protocols written by leading researchers in the field for assessing basic neutrophil functions, investigating specialized areas in neutrophil research, and completing step diagnostic assays of common neutrophil disorders. Topics covered include an overview of neutrophils and their role in host defense and inflammation; methods most commonly used for isolating neutrophils from humans and other...

Neutrophils, the most abundant white cells in humans, serve as the primary cellular defense against infection. Neutrophil Methods and Protocols, Second Edition provides a concise set of protocols written by leading researchers in the field for assessing basic neutrophil functions, investigating specialized areas in neutrophil research, and completing step diagnostic assays of common neutrophil disorders. Topics covered include an overview of neutrophils and their role in host defense and inflammation; methods most commonly used for isolating neutrophils from humans and other...

Neutrophil Methods and Protocols provides a concise set of protocols for assessing basic neutrophil functions, investigating specialized areas in neutrophil research, and completing step-by-step diagnostic assays of common neutrophil disorders. Each of the protocols is written by leading researchers in the field and includes hints for success, as well as guidance for troubleshooting. Parts 1 & 2 provide an overview of neutrophils the methods most commonly used for isolating them from humans and other animal species. Part 3 details methods for investigating adhesion, chemotaxis,...

Neutrophil Methods and Protocols provides a concise set of protocols for assessing basic neutrophil functions, investigating specialized areas in neutrophil research, and completing step-by-step diagnostic assays of common neutrophil disorders. Each of the protocols is written by leading researchers in the field and includes hints for success, as well as guidance for troubleshooting. Parts 1 & 2 provide an overview of neutrophils the methods most commonly used for isolating them from humans and other animal species. Part 3 details methods for investigating adhesion, chemotaxis,...