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Low back pain represents a significant concern in the United States, with 70% of individuals experiencing symptoms at some point in their lifetime. Symptoms of low back pain have been strongly associated with degeneration of the intervertebral disc. Insufficient nutritional supply is believed to be a major mechanism for disc degeneration. Thus, understanding nutrients transport in intervertebral disc is crucial to elucidate the etiology of disc degeneration, and to develop strategies for tissue repair, and tissue engineering. Transport phenomena in intervertebral disc are still...