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High-throughput and high-content analysis of cultured cells or even small organisms are of imminent importance in drug discovery, toxicology and in individualized medicine. In medicine, the identification of tailored patient-specific therapy is important in cancer, chronic inflammation, infection and other diseases. High Content Screening was developed with the perspective of the history of the development of the automated DNA sequencers that revolutionized the field of genomics. Furthermore, HCS was based on a history of important developments in modern cytology. Cell damage caused by free...