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The aging process involves changes in neurotransmission at different levels. The purpose of this book is to help define the state-of-the-art of the field and to give directives for future research on the aging brain. Following topics are presented: the comparison of normal and pathological aging at the anatomical and neurochemical level; the knowledge of the responses of the aging brain to drug treatment or environmental stress; the neuro/immune and neuro/endocrine setting during aging; and the definition of therapeutical approaches in normal aging. This book will interest physicians and...

Different molecular mechanisms cooperate to the regulation hormones, local metabolic of brain microcirculation: products, transmitterso Great interest has recently emerged in literature on the neuronal systems controlling the blood brain barrier and on the reciprocal interaction between neuronal activity and vascular supply. In particular, this volume on the NATO Advanced Research Workshop held in Salo' (BS), Italy, September 3-8, 1988, outlines the importance of neuron-vessel communication in the regulation of cerebral microenvironment. The problem is approached from a multidisciplinary...