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The role of T reg cells in chronic HCV infection highlights the application of their manipulations in HCV associated clinical situations. Their suppressive activityis limited to the biologically important compartment. Thus, the ratio of virus-specific CD8+ cells versus CD4+CD25+ T reg cells that is required for a strong suppression mirrors the intrahepatic situation. Assaying these cells marks the etiology of extrahepatic manifestations, asymptomatic MC in patients with chronic HCV and elucidate a correct way for treatment. Meanwhile, this book which is based on a research study conducted in...