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In metastasis, tumor cells disseminate from the primary lesion and home to secondary organs where they may remain dormant for a long time. Metastasis formation is still the most feared manifestation for tumor patients and clinicians. Although improvements have been made concerning earlier detection and specific therapy, most of the cancer patients still die of distant metastases. The purpose of these three volumes is to review the recent progress in molecular metas- tasis research and to attempt to further understand the biol- ogy of this multifocal process. With respect to present day...

In metastasis, tumor cells disseminate from the primary lesion and home to secondary organs where they may remain dormant for a long time. Metastasis formation is still the most feared manifestation for tumor patients and clinicians. Although improvements have been made concerning earlier detection and specific therapy, most of the cancer patients still die of distant metastases. The pu-rpose of these three volumes is to review the recent progress in molecular metas- tasis research and to attempt to further understand the biol- ogy of this multifocal process. With respect to present day...

Studienarbeit aus dem Jahr 2011 im Fachbereich BWL - Unternehmensfuhrung, Management, Organisation, Note: 2,3, FOM Hochschule fur Oekonomie & Management gemeinnutzige GmbH, Frankfurt fruher Fachhochschule, Sprache: Deutsch, Abstract: "Doch alle sind sie abgewichen, verkommen sind sie, alle miteinander, niemand ist da, der Gutes tut, nicht einmal einer " Dieses Zitat aus dem Alten Testament ist eine subjektive Darstellung eines Menschen-bildes. Seit jeher beschaftigen sich Wissenschaftler verschiedenster Fachgebiete mit den Fragen danach, ob der Mensch von Natur aus bose ist, bzw. was die...

Within the last decade the molecular biology of tumor models has revealed the identification of several metastasis- related molecules. These volumes attempt to review the most recent approaches of their mechanisms, regulation and way to treat their malignant alterations. The first volume covers the presentation of proteases and inhibitors and their role in invasion of tumor cells, also cell adhesion molecules and their interaction with the extracellular matrix. In the second volume the regulation of tumor progression and angiogenesis by cytokines, growth factors and motility factors is...

Although developments in wastewater treatment over recent decades have focused on the biological reactor, the secondary settling tank (SST) also plays a major role in achieving increasingly stringent effluent quality standards. This report collates many of the significant developments that have taken place in SST theory, design, modelling and operation. Earlier SSTs were designed only by empirical hydraulic criteria such as overflow rate, which do not recognize sludge concentration and settleability. Today, there are available not only much improved design procedures but also hydrodynamic...