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Age related changes in the lacrimal gland are associated with alterations in the structural organization and functional response in the gland of diverse mammalian species. The mechanisms behind age-related lacrimal gland dysfunction remain unclear due to the multifactorial and complex nature of this system. The present study is assigned to demonstrate the influence of aging on the structure of the lacrimal gland of albino rat and to provide a morphological basis to explain the pathogenesis of the dry eye syndrome with ageing. It aims also at carrying out a comparative analysis on...