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Appreciation of the importance of platelets and coagulation factors in therothrombotic events has led to the widespread use and continuous development of new antithrombotic agents. This field of cardiovascular pharmacology has advanced at a very rapid rate.

Understanding the basic principles of atherothrombosis as well as the pharmacological agents currently available or under clinical development are key to the successful treatment of patients with atherothrombotic manifestations, particularly coronary artery disease.