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A goal of periodontal diagnostic procedures is to provide useful information to the clinician regarding the existing periodontal disease type, location, and severity.Advances in oral and periodontal disease diagnostic research are moving toward methods whereby periodontal risk can be identified and quantified by objective measures such as biomarkers.Biomarkers of disease in succession play an important role in life sciences and have begun to assume a greater role in diagnosis, monitoring of therapy outcomes, and drug discovery. The challenge for biomarkers is to allow earlier detection of...