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A great deal of new information has been obtained during the past four years, and this monograph provides a clear and well reviewed update on biochemical mechanisms and the results of important new clinical studies using the interferons. Reviews include what is presently known about the biosynthesis, physiological role and mechanisms of action of the interferons (alpha, beta, gamma). New biochemical information on interferon-receptor interactions and signalling pathways is provided. The pharmacokinetic considerations in treating leukemia, lymphoma, myeloma, neuroendocrine tumors and other...

Palaeobiology: A Synthesis was widely acclaimed both for its content and production quality. Ten years on, Derek Briggs and Peter Crowther have once again brought together over 150 leading authorities from around the world to produce Palaeobiology II. Using the same successful formula, the content is arranged as a series of concise articles, taking a thematic approach to the subject, rather than treating the various fossil groups systematically.

This entirely new book, with its diversity of new topics and over 100 new contributors, reflects the exciting developments in the...