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This book will discuss the autonomic nervous system (ANS) from both an enlarged and a timed perspective. First, it presents how the organization of the ANS is hierarchical into different levels. Following that, the book discusses how the ANS changes functionally in the three-body configurations (wakefulness, slow sleep, rapid eye movement sleep) found in a 24-hour cycle. Finally, the most important clinical implications of this enlarged and timed vision of ANS will be discussed.

The ANS, in charge of the innervation of smooth muscle of all organs and of the heart, immune tissue and...

Rapa Nui, one of the world's most isolated island societies and home to the notable moai, has been at the centre of a tense debate for the past decade. Some see it as the site of a dramatic cultural collapse occurring before Western contact, where a self-inflicted ecocide was brought on by the exhaustion of resources. Others argue that the introduction of Western pathogens and the slave raids of 1862 were to blame for the near extinction of the otherwise resilient Rapa Nui people.　

Cultural and Environmental Change on Rapa Nui　brings together the latest...

As the title suggests, and unlike other existing books on sleep medicine, Neuroendocrine Correlates of Sleep/Wakefulness will be devoted primarily to endocrine regulation of the behavioral state control. It will address a wide spectrum of sleep./wakefulness phenomena (both animals and humans), including pathogenesis, diagnosis, and management.

From molecular biology to applied clinical therapy, sleep research has been transformed in the last few years from a research backwater to an important interdisciplinary field.

Anyone who regularly reads the literature on...

This timely work reflects the growing importance of research into the nature of sleep and its medical aspects. One of the first of its kind, this work on the neuroimmunology of sleep provides an introduction to the interplay between these two key and interlinked areas. Written both from a basic and a clinical perspective, the volume is an invaluable information resource for biomedical professionals and students of the human biology.

Highly practical guide written from both a basic and clinical perspective.

During the last few decades, Sleep Medicine and Science, and many of their diverse aspects, have emerged as areas of intense medical and scientific interest. Of these, Sleep and Neuroimmunology are highly interlinked and inherently fascinating which cut across many behavioral states, touches all facets of human health and wellbeing. Elucidating the roles of immune substances and cells in Central Nervous System functions and their critical relationships in immune mechanisms in health and diseases across behavioral states.

As one of the first of its kind, this Neuroimmunology of...