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The uniqueness of human architecture is based on interlinkages of the regulatory systems -neural, endocrine, immune, genetic- but the molecular mechanisms underlying this network are still incompletely understood. The endogenous indolergic system is considered as a protein-neuro-humoral-endocrine informational network resulted from the chemical and biological structure of some endogenous biomolecules with indole structure such as tryptophan, serotonin and melatonin. The endogenous privileged structures, such as the indole nucleus, can be used to develop active biological/therapeutic medical ...

In an era when information is the key to development and great innovation, the Pharmacology Annual Volume 2025 aims to connect the isolated islands of medical research and translate its outcomes into practical approaches for patients' benefit.
This volume brings together the scientific perspectives of pharmaceutical researchers, phytochemists, clinicians, and medical and drug specialists for a comprehensive view of the state of the art in pharmacology.
It is addressed to all professionals from academia, industry, pharmaceutical practice, and regulatory agencies as a valuable resource to...

This book provides a systematic and updated scientific perspective on the physiology of circadian rhythms, the molecular mechanisms of circadian entrainment, the pharmacological features derived from these signalling pathways, and their clinical outcomes. It offers a comprehensive perspective on the chronobiological impact on normal developmental processes, disruptive events that modulate the occurrence of diverse imbalances that sometimes imply disease, and the increasing importance of circadian rhythms in drug delivery.