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Both strategies for investigation (computational and experimental) in structural and mechanistic Enzymology have developed to some extent independently. However, over the last few years a trend has emerged for strengthening their integration. This combination not only brings together computations and experiments focused on the same enzymatic problems, but also provides complementary insights into the investigated properties and has a powerful synergy effect. This thematic volume of Advances in Protein Chemistry and Structural Biology focuses on the recent success in structural and...

In New York City in 2009, a new kind of public school opened its doors to its inaugural class of middle schoolers. Conceived by a team of game designers and progressive educational reformers and backed by prominent philanthropic foundations, it promised to reinvent the classroom for the digital age. Ethnographer Christo Sims documented the life of the school from its planning stages to the graduation of its first eighth-grade class. Disruptive Fixation is his account of how this "school for digital kids," heralded as a model of tech-driven educational reform, reverted to a more...

Weather Analysis and Forecasting: Applying Satellite Water Vapor Imagery and Potential Vorticity Analysis, Second Edition, is a step-by-step essential training manual for forecasters in meteorological services worldwide, and a valuable text for graduate students in atmospheric physics and satellite meteorology. In this practical guide, P. Santurette, C.G. Georgiev, and K. Maynard show how to interpret water vapor patterns in terms of dynamical processes in the atmosphere and their relation to diagnostics available from numerical weather prediction models. In particular, they...

Princess Lira is siren royalty and the most lethal of them all. With the hearts of seventeen princes in her collection, she is revered across the sea. Until a twist of fate forces her to kill one of her own. To punish her daughter, the Sea Queen transforms Lira into the one thing they loathe most--a human. Robbed of her song, Lira has until the winter solstice to deliver Prince Elian's heart to the Sea Queen and or remain a human forever.

The ocean is the only place Prince Elian calls home, even though he is heir to the most powerful kingdom in the world. Hunting sirens is more...