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This book examines the field of parallel database management systems and illustrates the great variety of solutions based on a shared-storage or a shared-nothing architecture.Constantly dropping memory prices and the desire to operate with low-latency responses on large sets of data paved the way for main memory-based parallel database management systems. However, this area is currently dominated by the shared-nothing approach in order to preserve the in-memory performance advantage by processing data locally on each server. The main argument this book makes is that such an unilateral...

This book describes developments in the field of super-resolution fluorescence microscopy or nanoscopy. In 11 chapters, distinguished scientists and leaders in their respective fields describe different nanoscopy approaches, various labeling technologies, and concrete applications. The topics covered include the principles and applications of the most popular nanoscopy techniques STED and (f)PALM/STORM, along with advances brought about by fluorescent proteins and organic dyes optimized for fluorescence nanoscopy. Furthermore, the photophysics of fluorescent labels is addressed, specifically...

This book describes developments in the field of super-resolution fluorescence microscopy or nanoscopy. The topics covered include the principles and applications of the most popular nanoscopy techniques STED and (f)PALM/STORM, along with advances brought about by fluorescent proteins and organic dyes optimized for fluorescence nanoscopy.