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The nematode Caenorhabditis elegans was used as an infection model to screen a random plasposon mutagenesis collection of 2500 mutants, derived from either Burkholderia cenocepacia K56-2 or J2315. This work focussed on the study of the P4A1 mutant derived from B. cenocepacia K56-2, carrying a Tn5 insertion interrupting the pbr gene, encoding a putative protein 50% identical to the stringent response regulator SocE of Myxococcus xanthus. Upstream of pbr, we identified two putative genes encoding proteins 97% and 91% identical, respectively, to the PhzD and PhzF from Pseudomonas chlororaphis,...

Recent advances in electrochemistry and materials science have opened the way to the evolution of entirely new types of energy storage systems: rechargeable lithium-ion batteries, electrochroms, hydrogen containers, etc., all of which have greatly improved electrical performance and other desirable characteristics. This book encompasses all the disciplines linked in the progress from fundamentals to applications, from description and modelling of different materials to technological use, from general diagnostics to methods related to technological control and operation of intercalation...

More than 140 bacterial small non-coding RNAs (sRNAs) have been discovered in Escherichia coli and other bacteria, most of them pathogenic. The sRNA genes are typically encoded in intergenic regions and range from 50 to 500 nucleotides long. Evidences accumulated over the last years point out that sRNAs act as major regulators of adaptive responses at the post-transcriptional level. The mechanisms by which sRNAs modulate the expression of its targets often involve the interaction with their mRNA targets, mediated by the Hfq protein a RNA chaperone. The RNA chaperone Hfq, has been...