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Prolactin is secreted from the anterior pituitary and is inhibited by tubero-infundibular dopamine neurons in the arcuate nucleus of hypothalamus. Abnormal electrical discharge passing through the hypothalamus may disrupt the normal functioning. Generalized neuronal discharge of a seizure stimulates the hypothalamus either directly, through specific neurotransmitter changes ( ed in GABA and dopaminergic system), or through the release of other substance, there by causing increase in serum prolactin during epileptic form seizures. Acute changes in serum prolactin levels which occurred...

Zinc is one of the most important trace elements that is required for proper growth and health. Being a cofactor of over 200 enzymes and a structural protein in a large number of zinc finger proteins, zinc serves a wide range of roles in human body. In our study Zinc level was found to be significantly decreased in febrile seizures in all previous as well as in present study. Since zinc levels were also found to be significantly low in patients with septic meningitis and cerebral malaria so better response may be expected if we supplement zinc preparation while continuing other treatment in...

The belief widely held in many countries is that a person with epilepsy is seized by a supernatural force or power. This ancient belief is reflected in the name of the disorder -- the word "epilepsy" being derived from the Greek word "epilambanein" which means "to seize or attack". We now know, however, that seizures are the result of sudden, usually brief, excessive electrical discharges in a group of brain cells (neurones) and that different part of the brain can be the site of such discharges. The clinical manifestations of seizures will therefore vary and depend on where in the brain the...