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This monograph deals with the impact of classical genetics in immunology, prov- ing examples of how large immunological questions were solved, and new fields opened to analysis through the study of phenotypes, either spontaneous or induced. As broad as biology has become, there are those who do not fully understand what the genetic approach is, and how it differs fundamentally from most of the methods available to natural scientists. They may hold the opinion that genetics has run its course since Mendel read his paper on peas in 1865. "Why bother with classical genetics," they may ask....

On occasion, the innate immune system is referred to as the "primitive" immune system. Perhaps this has dissuaded immu- nologists from analyzing it as energetically as they have analyzed the adaptive immune system during the past two decades. But while its phylogenetic origins are indeed ancient, and though it is "of the first type," there is nothing crude, nothing unsophisti- cated, and nothing "inferior" about innate immunity. On the contrary, the innate immune system has had time to achieve a level of refinement that is nothing short of dazzling, and a modicum of respect is at long last...

New developments in psychotherapy research and practice over the past twenty years require a new perspective from a psychotherapy book. Until recently, approaches to clinical practices were presented as competing truths. Each one was viewed as a distinct, all-encompassing system of thought and clinical practice. Therapists were expected to decide which school they favored and then apply its treatment methods consistently to all patients. This is no longer the case.
While a growing body of empirical research supports the efficacy of treatment over no treatment, it does not endorse any one...

This completely updated second edition of Comprehensive Textbook of Psychotherapy discusses the contemporary landscape of psychotherapy, honors its complexities, and focuses on history, theory, science, practice, and diversity. The book is divided into three parts: (1) Models of Psychotherapy; (2) Psychotherapy by Modalities and Populations, and (3) Research Methods and Randomized Clinical Trials, Professional Issues, and New Directions in Psychotherapy. Part 1 has been expanded to include two chapters on Interpersonal Psychotherapy (IPT). This section now details the similarities...

During the past decade, we have witnessed a dramatic transformation in the nature and uses of terrorism. In the 70s, it was often repeated that terrorists "want a lot of people watching, not a lot of people dead"; today, it is more accurate to say that terrorists want a lot of people dead, and even more people crippled by fear and grief. A major strategic intent of modern terrorists is to use larger scale physical attacks to cause stress in the general population. These changes in terrorist strategy have made it clear that we need better psychological and social responses to terrorism and...