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An already volatile eastside community becomes entrenched in community activism after the unwarranted murder of an African American youth. The youth-a standout athlete-is shot down in the streets under dubious circumstances by an officers questionable judgment, sparking civil unrest in the urban African American communities.

This book reviews understanding of the biological roles of extracellular molecular chaperones. It provides an overview of the structure and function of molecular chaperones, their role in the cellular response to stress and their disposition within the cell. It also questions the basic paradigm of molecular chaperone biology - that these proteins are first and foremost protein-folding molecules. Paradigms of protein secretion are reviewed and the evolving concept of proteins (such as molecular chaperones) as multi-functional molecules for which the term 'moonlighting proteins' has been...