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This study was designed to compare the pharmacokinetic parameters of Metronidazole in healthy volunteers and in human patients suffering from amebiasis (by confirming after Stool test). It was conducted in six healthy male volunteers and six male patients suffering from amoebiasis in Services Institute of Medical Sciences (SIMS), Lahore, Pakistan, all individuals were between the ages of 25-40 years. Both groups were treated with Metronidazole 500mg orally per individual. Blood samples were collected at 0, 0.25, 0.5, 1, 2, 3, 6, 12, 24 & 36 hrs after oral administration of Metronidazole....

This study was designed to compare the pharmacokinetic parameters of Levofloxacin in healthy volunteers and in human patients suffering from typhoid fever. The study was conducted in six healthy male volunteers and six male patients suffering from typhoid fever between the age of 25- 40 years. The patients were considered as group A and healthy volunteers were considered as group B. Both groups were treated with Levofloxacin 500mg tab orally. 5ml Blood samples were collected at 0, 0.25, 0.5, 1, 2, 3, 6, 12, 24, 36 & 72 hr from vein after oral administration. Plasma was separated by...