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BetaSys uses the example of regulated exocytosis in pancreatic -cells, and its relevance to diabetes, to illustrate the major concepts of systems biology, its methods and applications.

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BetaSys uses the example of regulated exocytosis in pancreatic β-cells, and its relevance to diabetes, to illustrate the major concepts of systems biology, its methods and applications.

Mathematics has for centuries been stimulated, financed and credited by military purposes. Some mathematical thoughts and mathematical technology have also been vital in war. During World War II mathematical work by the Anti-Hitler coalition was part of an aspiration to serve humanity and not help destroy it. At present, it is not an easy task to view the bellicose potentials of mathematics in a proper perspective.

The book presents historical evidence and recent changes in the interaction between mathematics and the military. It discusses the new mathematically enhanced development...

The authors consider a curve of Fredholm pair of Lagrangian subspaces in a fixed Banach space with continuously varying weak symplectic structures. Assuming vanishing index, they obtain intrinsically a continuously varying splitting of the total Banach space into pairs of symplectic subspaces. Using such decompositions the authors define the Maslov index of the curve by symplectic reduction to the classical finite-dimensional case. The authors prove the transitivity of repeated symplectic reductions and obtain the invariance of the Maslov index under symplectic reduction while recovering all...

This highly interdisciplinary volume brings together a carefully curated set of case studies examining complex systems with multiple time scales (MTS) across a variety of fields: materials science, epidemiology, cell physiology, mathematics, climatology, energy transition planning, ecology, economics, sociology, history, and cultural studies. The book addresses the vast diversity of interacting processes underlying the behaviour of different complex systems, highlighting the multiplicity of characteristic time scales that are a common feature of many and showcases a rich variety of...

Aside from the obvious statement that it should be a theory capable of unifying general relativity and quantum field theory, not much is known about the true nature of quantum gravity.

New ideas - and there are many of them for this is an exciting field of research - often diverge to a degree where it seems impossible to decide in which of the many possible direction(s) the ongoing developments should be further sustained.

The division of the book in two (overlapping) parts reflects the duality between the physical vision and the mathematical construction. The former is...

Elliptic boundary problems have enjoyed interest recently, espe- cially among C* -algebraists and mathematical physicists who want to understand single aspects of the theory, such as the behaviour of Dirac operators and their solution spaces in the case of a non-trivial boundary. However, the theory of elliptic boundary problems by far has not achieved the same status as the theory of elliptic operators on closed (compact, without boundary) manifolds. The latter is nowadays rec- ognized by many as a mathematical work of art and a very useful technical tool with applications to a multitude of...

Elliptic boundary problems have enjoyed interest recently, espe cially among C* -algebraists and mathematical physicists who want to understand single aspects of the theory, such as the behaviour of Dirac operators and their solution spaces in the case of a non-trivial boundary. However, the theory of elliptic boundary problems by far has not achieved the same status as the theory of elliptic operators on closed (compact, without boundary) manifolds. The latter is nowadays rec ognized by many as a mathematical work of art and a very useful technical tool with applications to a multitude of...