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Designing Healthcare That Works: A Sociotechnical Approach takes up the pragmatic, messy problems of designing and implementing sociotechnical solutions which integrate organizational and technical systems for the benefit of human health. The book helps practitioners apply principles of sociotechnical design in healthcare and consider the adoption of new theories of change. As practitioners need new processes and tools to create a more systematic alignment between technical mechanisms and social structures in healthcare, the book helps readers recognize the requirements of this...

Humans have "subdued 75 percent of the land surface, concocted a wizardry of industrial and medical marvels, strung lights all across the darkness." We tinker with nature at every opportunity; we garden the planet with our preferred species of plants and animals, many of them invasive; and we have even altered the climate, threatening our own extinction. Yet we reckon with our own destructive capabilities in extraordinary acts of hope-filled creativity: we collect the DNA of vanishing species in a "frozen ark," equip orangutans with iPads, and create wearable technologies and synthetic...

It is the late 1960s. Cold war tensions and the Vietnam conflict dominate the media. John Bluderin, a drafted, dejected nineteen-year-old army specialist, has been assigned to military intelligence in Germany. Fluent in German and absorbed into the social fabric of Schwabisch Gmund, no one would ever suspect him of doing anything out of the ordinary. Specialist Bluderin is about to prove everyone wrong.

As John begins his first assignment, he meets Leda Beschworung, a petite, dedicated agent able to jump twenty yards at a clip and infiltrate the enemy seamlessly. Leda, a practitioner of...

Antibody Fc is the first single text to synthesize the literature on the mechanisms underlying the dramatic variability of antibodies to influence the immune response. The book demonstrates the importance of the Fc domain, including protective mechanisms, effector cell types, genetic data, and variability in Fc domain function. This volume is a critical single-source reference for researchers in vaccine discovery, immunologists, microbiologists, oncologists and protein engineers as well as graduate students in immunology and vaccinology.

Antibodies represent the correlate of...