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The authors explained how various factors like aging, diet, socioeconomic status etc play important role in bringing about various physiological and biochemical changes in the body, which in turn disturb the genetic stability leading to malignancy. The current sample size being small could only be used as an indicator of the probable role of some of the major recognized risk factors causing the disease. The major chromosomal aberrations observed in the patients were similar to those reported in various tumor tissues and were indicative of the physiological stress of the tumor. Therefore,...

The rationale to carry out the present study was to look for the epidemiological factors, socio-demographic variables, anthropometric variables, biochemical parameters and chromosomal aberrations associated with Breast cancer in the Amritsar region and to compare the results with healthy unrelated controls to assess the risk factors associated with breast cancer in Amritsar region. The study was carried out during the period 2007-2011.During this hospital based study, epidemiological information was collected and biochemical investigations was carried in 261 subjects of Amritsar district; The...