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Diabetes is one of the major causes of death and disability in the world. The global figure ofpeople with diabetes is set to rise from the current estimate of 150 million to 220 million in 2010 and 300 million in 2025. Most cases will be of type II diabetes, with a sedentary lifestyle and obesi. A plethora of antidiabetic drugs are used in clinic, of which metformin hydrochloride is a very widely used and accepted drug. In spite of its favorable clinical response and lack of significant drawbacks, chronic therapy with metformin hydrochloride suffers from certain specific problems of which,...

Anticonvulsants are the drugs used in the treatment of experimentally produced seizers and antiepileptic are drugs used medically to control the epilepsies. Epilepsy is a disease due to central nervous system disorder which is characterized by seizures and convulsion or other abnormal body movements with loss of disorder of consciousness The purpose of research involving the synthesis of a series of novel derivatives for their anticonvulsant activity . The anticonvulsant activity of the synthesized compounds was established after intraperitoneal administration in mice which include maximal...