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This book covers both the technological development and biomedical applications of NADH fluorescence. Topics covered include perspectives on the history of monitoring NADH fluorescence, the relationship between mitochondrial function and other functions at the tissue level, responses of NADH to physiological and pathophysiological conditions, monitoring of NADH in the human brain and other organs, and metabolism. It also includes an in-depth look at flavoprotein (Fp) fluorescence and NADH in relation to redox state. This is an ideal book for biomedical engineers, researchers, and graduate...

This book covers both the technological development and biomedical applications of NADH fluorescence. Topics covered include perspectives on the history of monitoring NADH fluorescence, the relationship between mitochondrial function and other functions at the tissue level, responses of NADH to physiological and pathophysiological conditions, monitoring of NADH in the human brain and other organs, and metabolism. It also includes an in-depth look at flavoprotein (Fp) fluorescence and NADH in relation to redox state. This is an ideal book for biomedical engineers, researchers, and graduate...

This book focuses on energy metabolism and brain functions related to Cortical Spreading Depression of Leao (CSD), an important issue in brain pathophysiology. The first part of the book offers a comprehensive overview of the history and early research on CSD, and then discusses the recent advances in the technology used to map and monitor brain mitochondrial NADH redox state and other physiological functions during CSD. The chapters explore the connection between CSD and mitochondrial function under hypoxia, Ischemia and various drugs treatment, and provide a resource to scientists...