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Diabetes has become the most common single cause of end stage renal disease (ESRD) in most countries; this is due to the fact that diabetes, particularly type 2, is alarmingly increasing in prevalence rate, diabetic patients now live longer and patients with diabetic ESRD are now accepted for treatment in ESRD programs where formerly they had been excluded. About 20-30% of patients with type 1 or type 2 Diabetes develop evidence of nephropathy. Recent studies have now demonstrated that the onset and course of DN can be ameliorated to a significant degree if treatment is started at an early...