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prepare and evaluate mucoadhesive drug delivery system of Ranitidine hydrochloride tablet using hydrophilic polymers in order to reduce dose frequency to match the initial release of the drug with the conventional dosage form. The formulation was designed adopting optimization technique, which helps in setting up experiments in such a manner that the information is obtained as efficiently and precisely as possible. Initially, considering buoyancy as the main criteria, blank tablets were compressed for different formulae with various polymers HPMC K 15 M, HPMC K 100 M, Carbopol 934. The...

The purpose of this research was to prepare and characterize Aceclofenac microsphere of guar gum polymer for the application of inflammation. Method: - The microsphere were prepared by using emulsification method using starch cross-linked agent and coating was done by solvent evaporation method with the pH sensitive eudragit S-100 polymers. Result: -The prepared microsphere were white, free flowing and spherical in shape. The drug-loaded microsphere showed entrapment efficiency and drug release was extended upto 6 to 8 h. The infrared spectra, differential scanning calorimetry thermographs...