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This volume presents extensive research devoted to a broad spectrum of mathematics with emphasis on interdisciplinary aspects of Optimization and Probability. Chapters also emphasize applications to Data Science, a timely field with a high impact in our modern society. The discussion presents modern, state-of-the-art, research results and advances in areas including non-convex optimization, decentralized distributed convex optimization, topics on surrogate-based reduced dimension global optimization in process systems engineering, the projection of a point onto a convex set, optimal sampling...