Nutraceuticals for Alzheimer's disease: A Promising Therapeutic Approach

ISBN-13: 9789819906765 / Angielski

Arokiyasamy Justin Thenmozhi; Thamilarasan Manivasagam

Opis

This book reviews the potential effect of diet modification, lipids, and carbohydrate consumptions, vitamin supplementation, antioxidants, and nutraceuticals in the prevention and management of Alzheimer's disease. The initial chapter of the book presents the pathophysiological mechanisms, risk factors, genetic predisposition, disease diagnosis, pathology, and current treatment strategies against Alzheimer's disease. It also highlights recent developments in exploring novel compounds for the prevention and treatment of Alzheimer's disease. Subsequently, it highlights the therapeutic effect and regulation of molecular targets by natural compounds. The book discusses the potential of natural compounds in inhibiting the formation and deposition of Aβ peptides. It examines the natural compounds in modulating intracellular signaling molecules and enzymes involved in the pathogenesis of Alzheimer's disease. In summary, this book helps understand the role of natural compounds as a therapeutic approach in amelioration and preventing detrimental effects of Alzheimer's disease.

Spis treści

Chapter 1_Global Prevalance and Incidence of AD. - Chapter 2_Risk factors and Symptoms. - Chapter 3_Detailed Pathology of AD. -Chapter 4_Role of genetics in AD. -Chapter 5_Experimental models of AD. - Chapter 6_Current Pharmaceutical and non-pharmaceutical therapies for AD. - Chapter 7_Antioxidants and AD. - Chapter 7.1.1_Supplementation of Vitamin C, B &E. - Chapter 7.1.2_Extra virgin olive oil. - Chapter 7.1.3_Omega 3 fatty acids. - Chapter 7.1.4_N Acetyl cysteine. -Chapter 7.1.5_Pycnogenol. - Chapter 7.1.6_Baicalin. -Chapter 7.2_Fruits, vegetables, nuts and other natural products. - Chapter 7.2.1_Gingo biloba. - Chapter 7.2.2_Avocados. - Chapter 7.2.3_Grapes and wine. - Chapter 7.2.4_Cruciferous vegetable. - Chapter 7.2.4_Garlic & Onion. - Chapter 7.2.5_Leafy Greens. - Chapter 7.2.6_Tomato and lycopene. - Chapter 7.3_Fruits Chapter 7.3.1_Citrus fruits Chapter 7.3.2_Pomegranate Chapter 7.3.3_Berries. -Chapter 7.3.4_Figs Chapter 7.4_Nuts. -Chapter 7.4.1_Walnut. -Chapter 7.4.2_Almonds. -Chapter 7.4.3_Hazelnuts and Other nuts. -Chapter 7.5_Spices. -Chapter 7.5.1_Ginger. -Chapter 7.5.2_Pepper-Chapter 7.5.3_Cloves and asafoetida-Chapter 7.5.4_Nutmeg and cumin-Chapter 7.5.5_Turmeric and Cinnamon. -Chapter 8_Ayurvedic medicinal plants. -Chapter 9_Medicinal plants from Siddha system. -Chapter 10_Homeopathic plant remedies. -Chapter 11_Mediterranean diet and AD. -Chapter 12_Dietary Approaches to Stop Hypertension (DASH) diet. -Chapter 13_Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet. -Chapter 14_Fish-based diet and Low-copper diet. -Chapter 15_Foods increasing Gut microbiota. -Chapter 16_Foods reducing Constipation. -Chapter 17_Foods reducing risk factors for AD. -Chapter 18_Obstacles that negatively affect the efficacy. -Chapter 19_Dosage, side effects and toxicity. -Chapter 20_Limitations.

O autorze

Dr. A. Justin Thenmozhi is working as an Assistant Professor in the Department of Biochemistry, School of Biological Sciences, Madurai Kamaraj University, India. Earlier she served as an Assistant Professor in the Department of Biochemistry and Biotechnology, Annamalai University and Idhaya College for Women, Kumbakonam. She has an expertise in the field of Nutritional Neuroscience and Neuropharmacology and has published more than 60 research articles in peer reviewed international journals, has edited 2 books, and 21 book chapters in Neuroscience. Her books entitled “Food and Huntington’s disease” and “Food and Parkinson’s disease” were awarded as best books in the world by GOURMAND Cook Book Awards. She is the Fellow of “Academy of Sciences”, Chennai. She is holding membership in various international and national neuroscience societies. She has received the best researcher awards from the Annamalai University (2017- 2018 & 2018-2019) and has served as an editor/reviewer for various peer reviewed international journals including, Journal of Alzheimer’s disease, Neurochemical Research, Neurotoxicity Research, Chemico-Biological Interactions etc.

Dr. T. Manivasagam is an Assistant Professor in the Department of Biochemistry and Biotechnology, Annamalai University. His research interests are in neuroscience with specialization in cellular and animal models of Parkinson’s disease, Alzheimer’s disease and Autism, and drug discovery from plant products. He has published more than 100 research articles in the peer-reviewed international journals, edited 3 books, and authored or co-authored 50 book chapters. He has more than 15 years of teaching experience in Biochemistry and had received young scientist award from the Annamalai University and the Academy of Sciences, Chennai.