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Ethanolic & aqueous extracts of Ocimum sanctum, Tinospora cordifolia, Withania somnifera, Avicennia officinalis, Rhizophora mucronata & Shilajit were included in the present in vitro study. Pepsin was used as a substitute for HIV-protease to evaluate effect of these extracts, as pepsin has great structural and functional similarities with HIV-protease. Pepsin assay could be used for preliminary screening of natural products for probable HIV-protease inhibitory activity. The use of combination antiretroviral therapy has yielded clinical benefits for HIV-infected patients, however, it has also...

In the present in vitro study, Antimicrobial potential of Alum as well as its Bhasma- Sphatika Bhasma was evaluated against total 12 organisms, viz., 6 Gram Negative, 4 Gram Positive and 2 Fungi using various assays such as MIC, MBC/MFC and Agar Well Diffusion method. Alum as well as Sphatika Bhasma revealed broad spectrum Antibacterial activities inhibiting gram positive as well as gram negative organisms and moderate antifungal activities. Hence, Antibiofilm potential of Alum and Sphatika Bhasma was evaluated against total 10 bacterial biofilms using crystal violet staining method....