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Contrast nephropathy is a major and growing problem. It is the third most common cause of in-hospital acute renal failure and is associated with significant in-hospital mortality (20-30%, rising up to 62% for patients requiring emergency hemodialysis), long term mortality, increased risk of in-hospital major adverse cardiac events as well as with prolonged hospital stay and increased costs of health care. The incidence of contrast nephropathy is growing with the increasing use of radiographic contrast media for a variety of invasive procedures to diagnose and treat atherosclerotic...