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With the rising demand for complex, integrated and autonomous systems in the field of engineering, efficient and versatile Predictive Maintenance (PdM) frameworks have become a requirement for monitoring the health status of these systems since safety, reliability and optimum asset utilisation, are key issues. However, due to the continuously changing dynamics of industrial operations, the data recorded for developing PdM frameworks are often high-dimensional and characterised by undesirable features such as high level of uncertainty, class imbalance and multiclass among others. These...

Angiogenesis and Cardiovascular Disease provides a comprehensive review of the basic scientific and clinical advances in the field of angiogenesis, and its role in the human cardiovascular system. The material presented draws from multiple disciplines, integrating information in a single source. Topics addressed focus first on aspects of development and normal biology of the vasculature, and then on angiogenesis and how it is involved in the pathophysiology and therapy of ischemic cardiovascular disease. Vascular development, endothelial cell biology, the vascular matrix, and growth...

As International Investment Agreements (IIAs) continue to evolve and become increasingly complex, a key challenge for developing countries is how to maintain coherent investment obligations that are consistent across any overlapping treaty provisions. An even greater challenge is the effective negotiation of trade in services and investment commitments in Preferential Trade Agreements to make foreign investment supportive of development. This guide is designed to assist developing countries to negotiate IIAs that are more effective in promoting their sustainable development. It identifies...

As International Investment Agreements (IIAs) continue to evolve and become increasingly complex, a key challenge for developing countries is how to maintain coherent investment obligations that are consistent across any overlapping treaty provisions. An even greater challenge is the effective negotiation of trade in services and investment commitments in Preferential Trade Agreements to make foreign investment supportive of development. This guide is designed to assist developing countries to negotiate IIAs that are more effective in promoting their sustainable development. It identifies and...