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Inhaled Pharmaceutical Product Development Perspectives describes methods and protocols for developing inhaled pharmaceuticals while commenting on product development strategies and their suitability to support regulatory submission. It fills the gap between the aspirations of scientists invested in new technology development and the reality of the requirements that must be met for any new product to be commercialized.

The book brings together emerging analytical and inhalation technologies in a way that provides a unique perspective on formulation and device design,...

The interpretation of physical, chemical and biological phenomena as linear relationships between variables, or as simple functions of the variables, has been a significant scientific and mathematical strategy to their elucidation for centuries. It is often the case that the nature of linearity is to follow mathematical functions, e.g. power, exponential or logarithmic functions, nevertheless the desire to fit data to simple predictable expressions is imbued in every scientist and engineer. From a philosophical standpoint there is no reason to criticize this approach as it allows us to...

Provides a review of novel pharmaceutical approaches for Tuberculosis drugs

• Presents a novel perspective on tuberculosis prevention and treatment
• Considers the nature of disease, immunological responses, vaccine and drug delivery, disposition and response
• Multidisciplinary appeal, with contributions from microbiology, immunology, molecular biology, pharmaceutics, pharmacokinetics, chemical and mechanical engineering

With step-by-step methods of drug production and knowledge of major unit operations and key concepts of pharmaceutical engineering, this guide will help to improve communication among the varied professionals working in the pharmaceutical industry.

Key features:

REVISION OF A BESTSELLER - Updates include recent advances in the field to keep pharmaceutical scientists and technologists up-to-date

IDEAL INTRODUCTORY TEXT - Covers basic engineering principles, drug production, and development processes, so scientists can easily convert...

The pace of new research and level of innovation repeatedly introduced into the field of drug delivery to the lung is surprising given its state of maturity since the introduction of the pressurized metered dose inhaler over a half a century ago. It is clear that our understanding of pulmonary drug delivery has now evolved to the point that inhalation aerosols can be controlled both spatially and temporally to optimize their biological effects. These abilities include controlling lung deposition, by adopting formulation strategies or device technologies, and controlling drug uptake and...

The pace of new research and level of innovation repeatedly introduced into the field of drug delivery to the lung is surprising given its state of maturity since the introduction of the pressurized metered dose inhaler over a half a century ago. It is clear that our understanding of pulmonary drug delivery has now evolved to the point that inhalation aerosols can be controlled both spatially and temporally to optimize their biological effects. These abilities include controlling lung deposition, by adopting formulation strategies or device technologies, and controlling drug uptake and...

The authors cover particulate material, its form and production, sampling from bodies of powder, particle size descriptors and statistics, behavior of particles,...