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Depression is commonly thought of as a biological disorder best treated with antidepressant medications. Pharmaceutical companies and many experts promote this view as established in scientific fact. Here, Leventhal and Martell argue that there is scant actual scientific evidence for this view, and that the issue is open to considerable question. They maintain that there is very little known--they call the evidence woefully weak--regarding the role of biology in depression. Marketing by drug producers has not only led the public to accept dubious claims and over-value antidepressants, but...