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Galvani's Spark chronicles the gradual understanding of the nerve impulse which is the basis of all thoughts, sensations and actions. The story begins with Luigi Galvani's chance observation of a spark from a friction machine causing a frog's leg to twitch from across the room. The accurate recording and the understanding of the properties of the nerve fiber membrane that makes the impulse possible became the objectives of neuroscientists for over 200 years.

The author, Alan J. McComas finely interweaves the stories, the challenges, and the controversies of the most prominent...