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The objective of the present study was designed to establish more specific criteria for the degree of differentiation and nuclear DNA histochemical quantitation of OSCC. Morphometric measurements by image analysis computer system and DNA histochemical quantitative analysis were assessed in association with clinicopathological features of OSCC. Two histological grading systems were used; Broders' grading system & Invasive front grading system using four histomorphological features that includes; degree of keratinization, nuclear pleomorphism, pattern of invasion and host response (inflammatory...

Apoptosis has been recognized as a key mechanism of tumor cell elimination and in cancer, it has been recently assumed even with more importance with the realization that it may be the possible the principle mechanism by which irradiation and chemotherapy kill cancer cells. This study was to explore the role of apoptosis in dysplasia and squamous cell carcinoma of oral mucosa by detecting apoptotic influencing protein, procaspase-3 and cell death pathway genes, Fas and Fas ligand and antiapoptotic transcriptional factor, NFkB with c-myc oncogen.Forty-two selected cases were included in this...