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The International Symposium on Recent Advances in Nitric Oxide Research was held in Sapporo, Japan, in September 1997. Researchers from Japan and the United States met to share their most recent findings on the controversial function of NO in the human body. The papers contained in this volume, which were presented at the Sapporo Symposium, focus on newly discovered mechanisms of NO production and NO toxicity. The book consits of four parts: NO and Cell Function, NO and Circulation, NO Production, and NO and Liver. Included are reports of NO research in a number of areas of medical science...

The Sapporo International Symposium on "Recent Advances in Nitric Oxide Research" was held in Sapporo, Japan, in 1997, following the Fifth International Meeting on the Biology of Nitric Oxide in Kyoto, Japan, organized by Dr. Salvador Moncada, Dr. Noboru Toda, and Dr. Hiroshi Maeda. The field of nitric oxide research continues to expand rapidly, and our understanding of the physiological and pathophysiological roles of NO has increased greatly. The Kyoto Meeting was stimulating and informative, providing impetus for the Sapporo Symposium, which I had the great honor to organize. To...

Cardiovascular fluid mechanics is now used as a tool in determining diagnosis, treatment, and prognosis by physicians and surgeons working in the fields of cardiology and angiology. The text is based on a considerable amount of clinical and experimental data on blood flow in the heart and large vessels obtained using various methods such as ultrasound pulsed Doppler velocimetry (including Doppler color flow imaging), catheter-tip electromagnetic velocimetry, hot-film anemometry, and laser Doppler velocimetry. The book will introduce medical researchers and clinicians to this rapidly...

Remarkable progress has been made in understanding and treating heart failure. Among other developments, angiotensin-converting enzyme inhibitors and b-blockers have been found to have beneficial therapeutic effects, reinforcing the view that heart failure may be both a haemodynamic and a neurohumoral disorder. The Japanese Heart Failure Society was established to curb the threat of heart failure through research, education, and clinical practice. At the Society's "Annual Scientific Meeting", molecular biologists, physiologists, clinicians, surgeons, and researchers in related fields met to...