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The introduction part in this work presents a systematic and comprehensive survey of the methods of preparation and the chemical reactivity of cyanoacetamide derivatives. These compounds are important intermediates for the synthesis of a variety of otherwise difficulty accessible, synthetically useful and novel heterocyclic systems, for this reason. We focused our aim to use starting material possess a wide variety of potentially useful applications including biological, clinical and pharmacological areas. We found 4-aminoantipyrine (4AAP) possess the previously mentioned properties, so...

This book reported the literature survey of the chemistry of 2-cyanomethylbenzothiazole including the activity Syntheses and their synthetic importance. Furthermore, the obtained results were discussed, 41 novel compounds were synthesized, the synthetic mechanisms were investigated and compounds were established by elemental analysis and spectral data. The UV spectra of azo dyes provide additional evidence that such compounds have the hydrazone structure rather than the other structures. The newly synthesized compounds were screened for their antioxidant assay (ABTS method) and cytotoxicity...

This book is part of a program which deals with the design and synthesis of some new indole derivatives of pharmaceutical importance. The work aims to: (1) Explore and develop a new methodology for the synthesis of some novel heterocyclic compounds (pyrazolopyrimidine, pyrazole, imidazopyrazole, pyrazolodiazepine, pyrazolotriazine, and pyrazolothiadiazine) bearing an indole ring system. (2) Studying the reaction mechanism and elucidating the structure of these compounds by spectral data. (3) Studying the biological activity of these compounds as antioxidant agents using the ABTS method.