Phytochemical studies on Goniothalamus species

ISBN-13: 9783659646973 / Angielski / Miękka / 2015 / 80 str.

Li Fang Lim;Ahmad Fasihuddin;Wong Mui Hung

Opis

Goniothalamus uvarioides and Goniothalamus velutinus belonging to the Annonaceae family have been used in traditional medicine for the treatment of giddy, injury, diarrhea, aphrodisiac, body pain, cold, stomachache, swollen, headache, food poisoning, to maintain body health and as mosquito repellent. The phytochemical studies of G. uvarioides and G. velutinus were carried out. Two alkaloids, one styryllactone (styrylhydropyrone) and two flavonoids have been isolated. These compounds were characterized by spectroscopic analysis, chemical methods and by comparison with the published and data. The identified compounds were velutinum, aristolactam-BII from G. velutinus, and pinocembrin, goniothalamin as well as 5,7,4-trihydroxyflavanone (naringenin) from G. uvarioides. Compound S4 presented LD50 lower than 100 ppm while compound S5 showed LD50 lower than 10 ppm against Artemia salina. In addition, compound S5 displayed potent antibacterial activity towards Gram positive bacteria tested in the study.

O autorze

Has received Bachelor Science with Honors in Resource Chemistry in the year of 2002 and MSc degree in Natural Product Chemistry in 2007 from Universiti Malaysia Sarawak. Since 2007, an academician involved in curriculum development thus teaching various subjects related to physical, inorganic, organic and advanced organic chemistry.