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With increasingly complex analysis and dry-lab experiments in post genomic bio-informatics, the importance of computational tools for biologist and scientist has increased. Conventional software engineering practices including agile approaches are not suitable for evolutionary systems application development because of their peculiar characteristics ever evolving nature. In this research work we propose a a Prototype-based Software Development Methodology based on Prototype-based object modeling technique for developing agile software systems/applications. We feel that our ...