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Chemokines are a superfamily of low molecular weight cytokines that were initially described based on their ability to induce the directed migration of leukocytes to sites of inflammation or injury. In humans, there are approximately 45 chemokines that bind to 19 G-protein-coupled receptors. In addition to mediating cellular migration, chemokines have now been shown to affect many cellular functions including survival, adhesion, invasion, proliferation, and to regulate circulating chemokine levels. Although chemokine receptors were first described on leukocytes, it is now appreciated that...

Part 1 of this book deals with theoretical contributions of rough set theory, and parts 2 and 3 focus on several real world data mining applications. The book thoroughly explores recent results in rough set research.

In today's world, three great classes of non-infectious diseases - the metabolic syndromes (such as type 2 diabetes and atherosclerosis), the cancers, and the neurodegenerative disorders - have risen to the fore. These diseases, all associated with increasing age of an individual, have proven to be remarkably complex and difficult to treat. This is because, in large measure, when the cellular signaling pathways responsible for maintaining homeostasis and health of the body become dysregulated, they generate equally stable disease states. As a result the body may respond positively to a...

Access to Mobile Services focuses on methods for accessing broadcast based M-services from multiple wireless channels. This book presents a novel infrastructure that provides a multi-channel broadcast framework for mobile users to effectively discover and access composite M-services. Multi-channel algorithms are proposed for efficiently accessing composite services.

Access to Mobile Services provides an in-depth survey of wireless data access and motivates the need to treat mobile services differently. A wireless adaptation of Service Oriented Architecture (SOA) is also covered.

Television has become a ubiquitous part of our lives, and yet its impact continues to evolve at an extraordinary pace. The evolution of television from analog to digital technology has been underway for more than half a century. Today's digital technology is enabling a myriad of new entertainment possibilities. From jumbotrons in cyberspace to multi-dimensional viewing experiences, digital technology is changing television. Consequently, new advertising metrics that reflect the new viewer habits are emerging. The ability to capture a viewer's interactions changes the advertising...

Optical communication networks have played and will continue to play a prominent role in the development and deployment of communication network infrastructures. New optical systems and protocols will enable next generation optical networks to meet the diverse requirements from a wide range of new applications and services. Optical networks have evolved to become more flexible, intelligent and reliable. New optical switching architectures, technologies, and sophisticated control and management protocols have already enabled optical networks to be used not only in the core but also the...

Science and Engineering of Casting Solidification, Second Edition covers the essentials of solidification science of metals and alloys at macro- and micro-length scales at cooling rates specific to commercial castings and rapid solidification processing. The mathematical fundamentals necessary to build a working knowledge in the field, specifically partial differential equations and numerical analysis, are introduced. Each topic begins with the description of the underlying physics, followed by the mathematics required to build analytical and numerical models. Wherever...

The continuing development of various therapies to treat cancerous tumors has forced surgeons to reevaluate the role of radical surgery. This book explores how surgery, coupled with these therapies, can improve outcomes for patients with tumoral disease.

Are educators in Asia following primarily Western models in developing media education? This book sets out to understand the prevailing perspectives regarding media education in various Asian societies and aims to provide an Asian context to the debate.

Computational models can be found everywhere in present day science and engineering. In providing a logical framework and foundation for the specification and design of specification languages, Raymond Turner uses this framework to introduce and study computable models. In doing so he presents the first systematic attempt to provide computational models with a logical foundation.

Computable models have wide-ranging applications from programming language semantics and specification languages, through to knowledge representation languages and formalism for natural language semantics....

Like any goal-oriented procedure, experiment is subject to many kinds of failures. These failures have a variety of features, depending on the particulars of their sources. For the experimenter these pitfalls should be avoided and their effects minimized. For the historian-philosopher of science and the science educator, on the other hand, they are instructive starting points for reflecting on science in general and scientific method and practice in particular. Often more is learned from failure than from confirmation and successful application. The identification of error, its source, its...

Data Mining and Applications in Genomics contains the data mining algorithms and their applications in genomics, with frontier case studies based on the recent and current works at the University of Hong Kong and the Oxford University Computing Laboratory, University of Oxford. It provides a systematic introduction to the use of data mining algorithms as an investigative tool for applications in genomics. Data Mining and Applications in Genomics offers state of the art of tremendous advances in data mining algorithms and applications in genomics and also serves as an...

From its origins in the malachite mines of ancient Egypt, mining has grown to become a global industry which employs many hundreds of thousands of people. Today, the mining industry makes use of various types of complex and sophisticated equipment, for which reliability, maintainability and safety has become an important issue. Mining Equipment Reliability, Maintainability and Safety is the first book to cover these three topics in a single volume.

Mining Equipment Reliability, Maintainability and Safety will be useful to a range of individuals from...