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"chemical carcinogenesis" is the general title of the series of international meetings which are held, biannually, in sardinia (Italy) since 1981. Despite the generality of the title, the main effort of the scientific Committee has been to pursue a coherent line around one of the most distinguishing features of carcinogenesis: the "multifasic" development of the process. Given that many chemical compounds are known to cause "experimental cancer," many questions still remain unresolved or are given too simplistic answers. The very first question concerning the interaction between the chemical...

Carcinogenesis can be modulated by altering the physiological properties of the target parenchyma. Toxic cell injury, dietary, metabolic, or hormone imbalances may modify the course of chemical carcinogenesis, ultimately by altering the homeostasis of cell proliferation between the parenchymal cells