Vitamin K: Volume 78

ISBN-13: 9780123741134 / Angielski / Twarda / 2008 / 452 str.

Gerald Litwack

Opis

Vitamin K, one of the group of fat-soluble vitamins (A, D, E and K), has come into prominence lately because its activity as a blood coagulation factor impinges on the widespread occurrence of deep vein thrombosis in the human population especially in the older age group. This volume focuses, not only on the problem of blood coagulation and hypercoagulability, but upon the individual status of vitamin K in the human.

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists.

*Focuses on the problem of blood coagulation and hypercoagulability as well as bone metabolism and vascular biology
*In the category of basic science, contributions cover: VKOR1, the quinone reductases including structure, function and mechanism, vitamin K-dependent carboxylation, the actions of Gas6, vitamin K2-mediated apoptosis and other topics
*In the category of disease-related subjects, contributions cover warfarin therapy, diabetic nephropathy, bone health, including osteoporosis and tumor cell suppression, as well as other topics

Spis treści

CRYSTAL STRUCTURE OF HUMAN QUINONE REDUCTASE Gas6 GENE IN EARLY DIABETES VITAMIN K-DEPENDENT ?×-CARBOXYLATION VITAMIN K-DEPENDENT CARBOXYLATION DETERMINANTS OF VITAMIN K IN HUMANS VITAMIN K AND BONE CONDITION IN HUMAN ADULTS VITAMIN K DEPENDENT Gas6 ACTION CONGENITAL BLEEDING DISORDERS OF THE VITAMIN K DEPENDENT CLOTTING FACTORS DIAGNOSIS OF OSTEOPOROSIS QUINONE OXIDOREDUCTASES AND VITAMIN K METABOLISM DEEP VEIN THROMBOSIS AND VITAMIN K HEPATOCELLULAR CARCINOMA AND VITAMIN K VITAMIN K AND MITOCHONDRIAL TRANSMEMBRANE POTENTIAL NEW UNDERSTANDING OF THE VITAMIN K CYCLE AND ITS DOWNSTREAM PATHWAYSVKORC1 AND THE VITAMIN K CYCLE STRUCTURE AND FUNCTION OF VITAMIN K EPOXIDE REDUCTASE WARFARIN THERAPY AND VITAMIN K VKORC1 AND HUMAN CLOTTING FACTORS

O autorze

Dr. Litwack has authored 3 textbooks on biochemistry and hormones (one with John Wiley & Sons and 2 with Academic Press/Elsevier) and he has edited more than 70 volumes in the Vitamins & Hormones series (Academic Press/Elsevier); he has edited 14 volumes entitled Biochemical Actions of Hormones (Academica Press); He has edited (with David Kritchevsky) Actions of Hormones on Molecular Processes (Academic Press)