Trace Elements in Clinical Medicine: Proceedings of the Second Meeting of the International Society for Trace Element Research in Humans (Isterh) Augu

ISBN-13: 9784431681229 / Angielski / Miękka / 2012 / 504 str.

Hiroshi Tomita

Opis

The Second Meeting of the International Society for Trace Element Research in Humans (ISTERH) was held in Tokyo from August 28 through September 1,1989. On August 27, the day preceding the opening of the meeting, a typhoon made a direct attack on Tokyo, welcoming guests from all over the world in a rather violent way. To our great relief, the weather during the week of the meeting turned out to be exceptionally agreeable for that time of year in Tokyo. We were also pleased to see the entire scheduled course of the meeting, including the social activities, carried out smoothly and the contents of the program favorably appraised. The meeting was attended by 518 scientists from 30 countries. Recent unrest following steps toward democratization in the Communist bloc gave rise to some apprehension; therefore, we were particularly pleased to see attendants from China, Eastern Europe, and the Soviet Union. No one could possibly have predicted the drastic change in Eastern Europe that followed, but again, we were relieved to learn (by a subsequent letter) of the safety of an attendant from Rumania, who had been our greatest concern. A total of 384 papers were contributed to the meeting. The abstracts for all have been published in the Journal of Trace Elements in Experimental Medicine, vol 2, No. 2/3 (1989). This proceedings carries 64 subjects introduced in the Special Session.

Spis treści

Raulin Award Lecture.- Discovery of Human Zinc Deficiency and Marginal Deficiency of Zinc.- Neural Disorders.- Zinc in Taste and Smell Disorders.- Brain Aging and Trace Elements in Human: Clues into the Pathogenesis of Alzheimer’s Disease.- Zinc in Brain Development and Function.- Zinc Binding Peptides from Rat Brain.- Role of Zinc in the Peripheral Nervous System.- Cardiovascular Disorders.- Experimental and Epidemiological Studies on the Relation of Trace Elements in the Pathogenesis and Prevention of Cardiovascular Diseases.- Hepatic and Gastrointestinal Disorders.- Alcohol, Trace Elements, and Liver Dysfunction.- Regional Variations of Eight Trace Elements in Normal Human Liver.- The Role of Copper and Zinc as Pathogenic Factors in Liver Disease.- Zinc and Gastrointestinal Diseases.- Pathophysiological Significance of an Oral Zinc Tolerance Test in Patients with Chronic Hepatic Diseases.- Zinc Absorption in Normal Subjects and in Gastrointestinal Diseases.- The Relationship Between Plasma Iron Tolerance Curves and Fractional Intestinal Absorption of Iron.- Regulators of Iron Absorption in the Small Intestine.- Dialysis and Renal Disorders.- Aluminum Intoxication.- Search for the Unknown Trace Element Abnormalities in Uremia.- Neoplasma.- Selenium and Cancer.- Kinetics of Trace Elements in Cancer Patients.- Trace Elements in Cancer Diagnosis.- Trace Elements in Cancer Therapy.- Immunity.- Modulation of the Immune Response by Trace Elements.- Trace Element Regulation of Immunity and Infection.- Zinc and Thymulin.- Stress.- Effects of Exercise, Physical Trauma, and High Sugar Intake on Chromium, Copper, and Zinc Metabolism.- Zinc: The Role and It’s Implication in Clinical Surgery.- Total Parenteral Nutrition.- Trace Elements in Total Parenteral Nutrition.- Effect of Zinc Redistribution on Wound Healing during Total Parenteral Nutrition in Rats.- Clinical Study on Zinc Deficiency Receiving Total Parenteral Nutrition.- Molecular and Biochemical Aspects of Selenium Deficiency.- Platelet Glutathione Peroxidase Activity in Long-term Total Parenteral Nutrition with/without Selenium Supplementation.- Cardiomyopathy and Selenium Deficiency in a Caucasian Adolescent.- Drugs and Trace Elements.- Nephrotoxicities of Gold and Cisplatinum.- Drug-Induced Taste Disorder: Due to Zinc Chelation?.- Antiarthritic, Antiulcer, and Analgesic Activities of Copper Complexes.- Genetic Disorders.- Genetic Disorders of Copper Transport: Menkes’ Disease , Occipital Horn Syndrome, and Wilson’s Disease.- Prevention Possibility for Brain Dysfunction in Menkes’ Disease by Maternal Administration of Trace Elements.- Human and Canine Inherited Copper Toxicosis: Copper Balance Regulation and Molecular Genetics of Its Impairment.- Gene.- Finger-Loop Domains and Trace Metals.- Construction of Mouse Glutathione Peroxidase Gene and Its Expression.- The Role of Natural Opal Suppressor tRNA in Incorporation of Selenium into Glutathione Peroxidase.- Transcriptional Activation of Human and Yeast Metallothionein Genes by Heavy Metal Ions.- The Problems of Nutritional Requirement of Trace Elements.- Recommended Dietary Intakes of Trace Elements: Some Observations on Their Definition and Interpretation in Comparison with Actual Levels of Dietary Intake.- The Problems of Nutrition Requirements of Trace Elements: General Comments.- Trace Element Requirements and Dietary Intake Recommendations: With Specific Reference to the Third World.- Biochemical Characterization of Selenium Deficiency in China.- Ultratrace Elements: An Update.- The Influence of the Ultra Trace Element Deficiency (Mo, Ni, As, Cd, V) on Growth, Reproduction Performance and Life Expectancy.- Hormones and Vitamins.- Manganese as a Potential Modulator of Second Messenger Pathways.- Metabolism of Trace Metals in Ascorbic Acid Deficiency: With Special Regard to Zinc Metabolism.- Metal-Binding Proteins and Metalloenzymes.- Metallothionein: Biochemistry and Spatial Structure.- Metallothionein and Zinc Deficiency.- Synthesis and Properties of a Selenium Analogue of Metallothionein.- Transport of Copper.- New Analytical Techniques for Trace Elements.- ICP-MS-Application to Biological Samples.- Role of Reference Materials for Validation of Analytical Data in Trace Element Analysis of Biological Materials.- A Guideline for Application of Neutron Activation Analysis to Biological and Medical Samples.- Summary of New Analytical Techniques and General Discussion.- Environment and Trace Elements.- Aluminum Toxicity in Humans.- Methylmercury Toxicity.- Advances in the Toxicology of Inorganic Mercury.- Current Topics on the Toxicology of Inorganic Lead.- Cadmium Accumulation in Human Tissues: Relationship to Development of Toxic Effects.- Factors Aggravating Cadmium Health Effects in Old Animals.- Author Index.- Key Word Index.

O autorze

An account of the latest research and clinical findings on trace elements. The information touches all areas of clinical medicine.