Toxicological Risk Assessment of Chemicals: A Practical Guide

ISBN-13: 9780849372650 / Angielski / Twarda / 2008 / 448 str.

Ostergaard Ostergaard; Grete Ostergaard; Elsa Nielsen

Opis

Unlike many existing books on toxicology that cover either toxicity of a particular substance or toxicity of chemicals on particular organ systems, Toxicological Risk Assessment of Chemicals: A Practical Guide lays out the principle activities of conducting a toxicological risk assessment, including international approaches and methods for the risk assessment of chemical substances. It illustrates each step in the process: hazard identification, a dose response assessment, and exposure assessment. The book also summarizes the basic concepts of interaction of chemicals in mixtures and discusses various approaches to testing such mixtures. Features:

• Addresses standards from all international regulatory agencies
• Presents the steps in risk assessment, including hazard identification, exposure assessment, and risk characterization
• Covers the assessment of multiple chemical exposures or chemical mixtures
• Contains data from both human and animal studies
• Explains the linearized multi-stage mathematical model widely used by the US EPA for characterizing

Spis treści

Introduction. Data for Hazard Identification and Characterisation. Hazard Assessment. Exposure Assessment. Risk Characterisation. Combination Effects.

O autorze

Elsa Nielsen, Grete Ostergaard, John Christian Larsen