Toxicoepigenetics: Core Principles and Applications

ISBN-13: 9780128124338 / Angielski / Miękka / 2018 / 428 str.

Shaun D. McCullough; Dana Dolinoy

Spis treści

1. The Role of Histone Acetylation and Acetyltransferases in Gene Regulation 2. The Role of Histone Methylation and Methyltransferases in Gene Regulation 3. Linking Chromatin Accessibility with Exposure Effects and Susceptibility 4. Implications for Chromatin Biology in Toxicology 5. The Role of DNA Methylation in Gene Regulation 6. Implications of DNA Methylation in Toxicology 7. DNA Methylation as a Biomarker in Environmental Epidemiology 8. DNA Hydroxymethylation: Implications for Toxicology and Epigenetic Epidemiology 9. The Role of Non-Coding RNAs in Gene Regulation 10. miRNAs and lncRNAs as Biomarkers of Toxicant Exposure 11. Germline and Trans-generational Impacts of Toxicant Exposures 12. Novel Bioinformatics Methods for Toxicoepigenetics 13. Incorporating Epigenetics into Risk Assessment Frameworks 14. Chromatin Immunoprecipitation: General Protocol and Considerations for Analysis 15. Methods for Analysis of DNA Methylation 16. Methods for Analyzing miRNA Expression