The Transplantation and Replacement of Thoracic Organs: The Present Status of Biological and Mechanical Replacement of the Heart and Lungs

ISBN-13: 9789401068055 / Angielski / Miękka / 2011 / 640 str.

D. K. Cooper; Dimitry Novitzky

Opis

It gives us great pleasure to contribute a short introduction outstanding book. This comprehensive work provides an to this important volume. immense fund of information, and will be an invaluable The transplantation of thoracic organs - heart, heart source of knowledge to physicians, surgeons, and scientists lung, lung - is a field of surgery that is expanding annually. for many years to come. The use of mechanical assist devices and artificial hearts to support patients awaiting transplantation is also developing rapidly, and further advances in this field may eventually April 1990 Christiaan Barnard lead to a totally implantable device that will function Cape Town, South Africa successfully for many years. It is therefore timely that such a volume as this should be made available to those who wish to be brought up-to date with the current state of knowledge in these related fields. The editors have done us all a great service in bringing together experts in every aspect of heart and Nazih Zuhdi lung transplantation and replacement to contribute to this Oklahoma City, USA Xl Preface The fields of the transplantation and replacement of thoracic Refinements in bioengineering have enabled mechanical organs have expanded immensely since the first human assist devices and the total artificial heart to support patients to-human heart transplant was performed in 1967. This successfully until a suitable donor becomes available."

Recenzje

'The book offers and immense fund of information to all physicians and surgeons wishing to keep abreast to developments in the field of thoracic organ transplantation.' International Surgery 77:4 1992

Spis treści

Section I: Orthotopic And Heterotopic Heart Transplantation.- 1 Experimental development and early clinical experience.- 2 Indications, selection and management of the recipient.- 3 The concept and diagnosis of brain death.- 4 Medico-legal aspects.- 5 Donor organ availability and transplant coordination.- 6 Selection and management of the donor.- 7 Storage of the donor heart.- 8 Pretransplant immunological considerations.- 9 Anesthetic management including cardiopulmonary bypass.- 10 Surgical technique of orthotopic heart transplantation.- 11 Surgical technique of heterotopic heart transplantation.- 12 Immediate postoperative care and maintenance immunosuppressive therapy.- 13 Physiology and pharmacology of the transplanted heart.- 14 Immunobiology of allograft destruction.- 15 Pathology of acute rejection.- 16 Diagnosis and management of acute rejection.- 17 Infectious complications.- 18 Pathology of graft atherosclerosis (chronic rejection).- 19 Diagnosis and management of graft atherosclerosis (chronic rejection).- 20 Retransplantation.- 21 Malignant neoplasia in the immunocompromised patient.- 22 Other complications of transplantation and immunosuppressive therapy.- 23 Heterotopic heart transplantation — indications and special considerations.- 24 Heart transplantation in infants and children — indications and special considerations.- 25 Psychiatric aspects.- 26 Medico-social aspects.- 27 Nutrition and diet.- 28 Exercise rehabilitation.- 29 Non-cardiac surgery in patients with heart transplants — anesthetic and operative considerations.- 30 Non-cardiac autopsy findings in patients with heart (or heart—lung) transplants.- 31 Results of cardiac transplantation and factors influencing survival. 1. International Society for Heart Transplantation Registry.- 32 Results of cardiac transplantation and factors influencing survival. 2. Collaborative Heart Transplant Study.- Section II: Transplantation Of The Heart And Both Lungs.- 33 Experimental background and early clinical experience.- 34 Indications, selection, and management of the recipient.- 35 Selection of the donor; excision and storage of donor organs.- 36 Anesthetic management.- 37 Surgical technique of the recipient operation.- 38 Postoperative management, surgical complications, diagnosis and management of acute rejection.- 39 Immunological aspects.- 40 Pathology of heart—lung transplantation.- 41 Infectious complications.- 42 Physiology and pharmacology of the transplanted lungs.- 43 Diagnosis and management of bronchiolitis obliterans (chronic rejection): retransplantation.- 44 Results of heart—lung transplantation and factors influencing survival.- Section III: Single And Double Lung Transplantation.- 45 Experimental background and early clinical experience.- 46 Indications, selection and management of the recipient.- 46 Selection of the donor: excision and storage of the lungs.- 48 Anesthesia for single lung transplantation.- 49 Surgical technique of single lung transplantation.- 50 Surgical technique of double lung transplantation.- 51 Postoperative management.- 53 Complications.- 54 Results of lung transplantation.- Section IV: The Role Of Mechanical Support Devices In Cardiac Transplantation.- 54 Indications and selection of cardiac support device.- 55 Non-pulsatile centrifugal pumps.- 56 Pulsatile ventricular assist devices.- 57 Total artificial hearts.- 58 Results of mechanical circulatory support as a ‘bridge’ to cardiac transplantation — Combined Registry Report.- Section V: Permanent Cardiac Replacement By The Total Artificial Heart.- 59 Experimental background and current problems.- 60 Clinical experience.- Section VI: Cardiac Xenotransplantation.- 61 Xenotransplantation: overview.- 62 Pathology of xenograft rejection.- 63 Mechanisms and possible management of hyperacute (vascular, humoral) or xenograft rejection.- 64 Clinical experience.- Section VII: Cardiac Augmentation With Skeletal Muscle.- 65 Cardiomyoplasty.- 66 Blood pumps constructed from skeletal muscle.- Section VIII: The Future Of Thoracic Organ Replacement.- 67 Some ethical and logistic issues in transplantation.- 68 Heart and lung replacement: future perspectives.