The Superoxide-Forming NADPH Oxidase of Phagocytes: An Enzyme System Regulated by Multiple Mechanisms

ISBN-13: 9783662311561 / Angielski / Miękka / 2014 / 338 str.

Dr. med. Roland Seifert;Professor Dr. med. Günter Schultz

Opis

The book reviews the literature on the regulation of NADPH oxidase, which is controversial in many areas, and refers specifically to relevant publications from the past 4 years. Main topics are catalytical properties, cofactor requirements and structural components of NADPH oxidase, activation of NADPH oxidase, inhibition of NADPH oxidase, reconstitution and regulation of NADPH oxidase activity in cell-free systems, and pathology of NADPH oxidase.

Spis treści

NADPH Oxidase: A superoxide-forming enzyme system.- Activation of NADPH Oxidase.- Inhibition of NADPH Oxidase.- Reconstitution and regulation of NADPH Oxidase activity in cell-free systems.- Pathology of NADPH Oxidase.- Age- and sex-ralated alterations of the activity of NADPH Oxidase.- Concluding remarks.