The Enzymes: Protein Methyltransferases Volume 24

ISBN-13: 9780121227258 / Angielski / Twarda / 2006 / 570 str.

Steven G. Clarke; Fuyuhiko Tamanoi

Opis

Protein methylation has recently emerged as one of the most exciting areas of study on posttranslational modification. A large family of protein methyltransferases has been identified and their structural properties have been characterized. These studies have provided novel insights into how methylation regulates a variety of biological functions including DNA and RNA metabolism, protein synthesis and signal transduction. Methylation also plays important roles in aging. This volume is intended to capture these recent developments concerning protein methyltransferases.

Spis treści

Part I: Overview of Protein Methyltransferases
Part II: Modification of Lysine and Arginine Residues in Signal Transduction, Transcription Translation, and Other Functions
Part III: Biological Regulation by Protein Methyl Ester Formation
Part IV: Recognition of Damaged Proteins in Aging by Protein Methyltransferases
Part V: Modification of Proteins by Methylation of Glutamine and Asparagine Residues
Part VI: Inhibition of Metyltransferases by Metabolites

O autorze

Fuyu Tamanoi is a biochemist who has served on the UCLA School of Medicine and UCLA College faculty since he joined the Department of Microbiology, Immunology & Molecular Genetics in 1993. He became a full professor in 1997.