The Circadian Clock

ISBN-13: 9781461425120 / Angielski / Miękka / 2012 / 300 str.

Urs Albrecht

Opis

The purpose of this volume is to provide historical and current information about the circadian clock, molecular properties of clock components and their roles in health and disease. It offers an integrated view how an organism is organized over 24 hours.

Spis treści

Contributors Preface A History of Chronobiological Concepts S. Daan Transcriptional Regulation of circadian clocks J. A. Ripperger, S. A. Brown Posttranslational Regulation of Circadian Clocks J. T. Vanselow, A. Kramer Non-Image Forming Photoreceptors S. N. Peirson, R. G. Foster Circadian Clocks and Metabolism H. Oster Circadian Clock, Cell Cycle and Cancer Z. Zhao, C. C. Lee Comparative Clocks M. Merrow, D. Lenssen, T. Roenneberg Circadian Neuronal Networks E. D. Herzog, P. H. Taghert The Circadian Clock and the Homeostatic Hourglass – Two Timepieces Controlling Sleep and Wakefulness S. L. Chellappa, C. Cajochen Clocks, Brain Function, and Dysfunction C. Feillet, U. Albrecht Systems Biology and Modeling of Circadian Rhythms T. d’Eysmond, F. Naef Index

Blurb

This comprehensive book, written by experts in the field, provides historical and current information about the circadian clock, molecular properties of clock components and their roles in health and disease. The Circadian Clock includes advances in several aspects of clock research with chapters ranging from gene expression, mathematical modeling, physiology, neuroscience and comparitive biology. It aims to give an integrated view how the biochemistry and physiology of an organism is organized over the 24 hours of a day and how disturbance of clock function can lead to disease. The Circadian Clock is an ideal book for researchers, clinicians and graduate students in the fields of biochemistry, cell biology, physiology, neuroscience and bioinformatics.