The Chemokines: Biology of the Inflammatory Peptide Supergene Family II

ISBN-13: 9781461362838 / Angielski / Miękka / 2012 / 227 str.

I. J. D. Lindley; J. Westwick; S. Kunkel

Opis

The first symposium in this series was held at the Royal College of Surgeons of England in December 1988 and was entitled "Novel Neutrophil Stimulating Peptides." That symposium successfully brought together the majority of laboratories working in the area of interleukin-8 and related peptides; see Immunology Today 10: 146-147 (1989). The Second International Symposium on Chemotactic Cytokines was held at the same venue in June 1990, and a much-increased attendance reflected the accelerating pace of work in the area of these chemotactic cytokines. The proceedings of that meeting were published in Advances in Experimental Medicine and Biology, vol. 305 (1991). The rapid advances made in the field of chemotactic cytokines over the last 18 months necessitated a third Symposium in this series to collate and place in perspective an explosion of new data. The Third International Symposium on Chemotactic Cytokines was held between August 31 and September 1, 1992 in Baden-bei-Wien, Austria. However, the lack of a clear nomenclature system was creating some confusion in the area, especially as new factors continue to be discovered and classified as family members. In the past, these inflammatory mediators had been placed arbitrarily under the broad heading of "intercrines" or "chemotactic cytokines" with no clear classification guidelines to follow. This nomenclature issue was addressed at the Symposium, where investigators in the field were invited to reach a consensus regarding a collective name for these mediators. The resulting decision was to identify the major family as chemokines, to replace all previous terms.

Spis treści

Symposium Presentations.- Chemotactic and Inflammatory Cytokines: CXC and CC Proteins.- Induction of Chemotactic Cytokines by Minimally Oxidized LDL.- The Immunopathology of Chemotactic Cytokines.- Receptor/ligand Interactions in the C-C Chemokine Family.- Adhesion Molecules in Acute and Chronic Lung Inflammation.- Monocyte Chemotactic Protein-1 (MCP-1): Signal Transduction and Involvement in the Regulation of Macrophage Traffic in Normal and Neoplastic Tissues.- Secretion of Monocyte Chemoattractant Protein-1 (MCP-1) by Human Mononuclear Phagocytes.- L-arginine/nitric Oxide Pathway: A Possible Signal Transduction Mechanism for the Regulation of the Chemokine IL-8 in Human Mesangial Cells.- Some Aspects of NAP-1/IL-8 Pathophysiology II: Chemokine Secretion by Exocrine Glands.- Molecular Mechanisms of Interleukin-8 Gene Expression.- Basophil Activation by Members of the Chemokine Superfamily.- Monocyte Chemotactic Proteins Related to Human MCP-1.- Platelets Secrete an Eosinophil-chemotactic Cytokine which is a Member of the CC Chemokine Family.- Neutrophil-activating Peptide ENA-78.- The Effects of Human Recombinant MIP-1?, MIP-1? and RANTES on the Chemotaxis and Adhesion of T Cell Subsets.- Promiscuity of Ligand Binding in the Human Chemokine Beta Receptor Family.- Structural and Functional Characterization of the Interleukin-8 Receptors.- Elucidation of Structure Function Relationships in the IL-8 Family by X-ray Crystallography.- Overview of Chemokines.- Abstracts.- Regulation of Cytokine Secretion by Poxvirus Encoded Proteins.- Interleukin-8 Expression in Gastric Cancer.- Synergistic IL-8 Synthesis by Human Peritoneal Mesothelial Cells (HPMC) Following IL-1? and TNF? Treatment.- Detection of a Potent Chemotactic Activity in Supernatants from Human Monocytes Stimulated with Endothelin-1.- Glioblastoma Secrete MCP-1, a Monocyte Chemotactic Factor.- Neutrophil Chemotactic Activity in the Bronchoalveolar Lavage Fluid of Asthmatics.- The Chemoattractant Properties of Interleukin-4.- IL-8 Induced Chemotaxis of Peripheral Neutrophils in Children with Cystic Fibrosis (CF).- Unusual Properties in Vitro and in Vivo of 198, an Antibody that Recognizes Rabbit CD11b.- Effect of Monocyte Chemotactic Cytokine Gene Transfer on Macrophage Infiltration, Growth and Metastatic Behaviour of a Murine Melanoma.- Expression of Monocyte Protein 1 (MCP-1) by Monocytes and Endothelial Cells Exposed to Thrombin.- IL-8 Production During Urinary Tract Infections.- NAP-1/IL-8 Receptor Expression on Human Neutrophils.- Macrophage-derived Neutrophil Chemotactic Factor (MNCF) Induces Neutrophil Migration Through Lectin-like Activity.- Interleukin-8 Release from Human PMN is Modified by Airborne Particulated Matter.- Interleukin-8 Induces the Expression of HLA-DR Antigen on Human Keratinocytes.- Cloning, Sequencing and Expression of Ovine Neutrophil-attractant Protein-1/IL-8 and Monocyte Chemoattractant Protein-1.- Inhibition of LPS-mediated Responses in Human Whole Blood by Recombinant Bactericidal/Permeability Increasing Protein.- The Activity of IL-8 in Combination with GMCSF and TNF?.- Induction of IL-8 in Inflammatory Bowel Disease.- Elevated Circulating and Tissue IL-8 in Alcoholic Hepatitis.- Expression of Monocyte Chemoattractant Protein-1 in Basal Keratinocytes of Psoriatic Lesions.- IL-8 Concentration in ?-Thalassaemia and after Bone Marrow Transplantation.- Cytokine Production in Felty’s Syndrome.- The Lymphocyte Attractant Effects of Interleukins la and 8 Are Not Due to the Release of a Secondary Chemoattractant Factor.- Serial Changes in Circulating Interleukin-8 and Neutrophil Elastase After Major Surgery.- Role of Interleukin-8 in the Pathogenesis of Neutrophil-mediated Acute Lung Injury.- Interleukin-8 in Severe Meningococcal Infections: Correlation with Severity of Disease.- IL-6 and IL-8 Levels in Patients with Rheumatoid Arthritis.- Plasma Interleukin 8 Levels in Patients with Septic Shock.- Inhibitory Effect of Protease-inhibitor for Production of Interleukin 8 (IL-8) and Polymorphonuclear Leukocyte Elastase (PMNE).- Effect of Diluents and Capture Antibodies on Detection of NAP-1 by Sandwich ELISA.- Do the Two Types of IL-8 Receptor on Human Neutrophils Mediate Different Cellular Responses?.- Interleukin 8 Plays a Fundamental Role in Inflammatory Processes in Vivo.- Endothelial Cell Binding of NAP-1/IL-8: Role in Neutrophil Emigration.- Heparin Binding of NAP-1/IL-8: The Effect of Heparin and Related Glycosaminoglycans on in Vitro Neutrophil Responses to NAP-1/IL-8.- The Effect of 5-Lipoxygenase Inhibitors on the Activity of IL-8.- Chemotactic Cytokine Generation by Human Lung Microvascular Endothelial Cells: Differential Regulation by Gamma Interferon..- The Effect of Haemofiltration on Circulating Cytokines in Children Undergoing Cardiopulmonary Bypass: A Preliminary Study.- Interleukin-8 (IL-8) is Produced by the Bronchoalveolar Lavage Cell Population from Patients with Active but not Inactive Sarcoidosis..- Gastric Interleukin-8 and Interleukin-8 IgA Autoantibodies in Helicobacter pylori Infection.- Eosinophils from Allergic Individuals, but not Normal Individuals, Show Chemotactic Responsiveness to NAP\IL-8.- Monocyte Chemotactic Peptide-1 and NAP-1/IL-8 Formation in Baboon Septicemia are Partially TNF Dependent.- Increased Expression of Monocyte Chemoattractant Protein-1 (MCP-1) in Glomeruli from Rats with Anti THY 1.1 Glomerulonephritis.- Role of Macrophage Inflammatory Protein (MIP) –1? in Granulomatous Inflammation.- NAP-1/IL-8 is a Weak Inducer of T Cell Migration into Skin.- IL-8 Stimulated Lymphocyte Locomotion in Antigen-or Mitogen-activated Mononuclear Cell Cultures.- In Vivo Studies of Rantes and the Recruitment of Lymphocytes to Inflammatory Sites.- IL-1 and TNF Induced Upregulation of IL-8 Receptors on Human Epidermal Cells.- Promiscuity of Ligand Binding in the Chemokine Beta Receptor Family.- Differentiation-specific Expression of a Novel G Protein-coupled Cytokine Receptor from Burkitt’s Lymphoma.- Signal Transduction by Monocyte Chemotactic Protein-1 (MCP-1) and Cross-desensitization with Other Members of the Chemokine-? Subfamily in Human Monocytes.- Mechanisms of Zymosan-induced IL-8 Generation in vivo.- The Effects of Intranasal Challenge with Interleukin-8 (IL-8).- Interleukin-8 Down-regulates the Oxidative Burst Induced by Tumor Necrosis Factor Alpha in Neutrophils Adherent to Fibronectin.- Identification of a Novel Tumor-derived Monocyte Chemotactic Factor: Relationship with Tissue Inhibitor of Metalloproteinase.- ?-Melanocyte Stimulating Hormone Inhibits Human Epidermal Cell and Polymorphonuclear Leukocyte Chemotaxis.- MIP-1 ?: A Potent Stem Cell Inhibitor.